4.8 stars from 10,000+ reviews

The World's First Nano-Hydroxyapatite Oral Spray.

Strengthens teeth and improves cavity protection by 62% in just 3 minutes

Tooth decay (caries) affects 2.5 billion people worldwide — and your mouth’s acidic pH is the reason. Our dentist developed formula rebuilds teeth at the molecular level and neutralizes the acids that destroy them — giving you protection anytime, anywhere.

TRY CARISPRAY

Dentistformulated

Patent-Pending Technology

Clinically-Proven

Completely safe

 4.8 stars from 10,000+ reviews

The World's First Nano-Hydroxyapatite Oral Spray.

Strengthens teeth and improves cavity protection by 62% in just 3 minutes

Tooth decay (caries) affects 2.5 billion people worldwide — and your mouth’s acidic pH is the reason. Our dentist developed formula rebuilds teeth at the molecular level and neutralizes the acids that destroy them — giving you protection anytime, anywhere.

TRY CARISPRAY

Dentistformulated

Patent-Pending Technology

Clinically-Proven

Completely safe

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

🦷 Healthy Smiles

🌟 Proven Results

💧 Gentle Care

TRANSFORM YOUR ORAL HEALTH

Clinically proven, patent-pending technology with nano-hydroxyapatite remineralization helps protect against cavities before they start.

Restores Natural Whiteness

Revives your smile’s natural shine without harsh abrasives.

Smooth and Relief

Gently soothes irritation and keeps teeth feeling silky smooth.

Smooths & Protects

Creates a protective barrier to prevent future damage and decay

Advanced Cavity Protection

Helps prevent cavities and keeps young teeth strong.

Sensitivity Support

Calms sensitive teeth while reinforcing enamel defenses.

Enamel Remineralization

Strengthens and rebuilds tooth enamel for lasting protection.

CariSpray ingredients nano-hydroxyapatite xylitol pH balancing system

Everyday Protection for Little Teeth

Snacks, sips, and night feedings create acid that attacks enamel all day long — brushing can’t keep up.

pH+ Technology

Rebuilds and strengthens enamel with fast-acting calcium and phosphate ions

Works While They Sleep

Long-lasting, no-rinse formula for overnight protection

25% Xylitol Base

Balances oral pH and supports natural saliva defense

Zero Cooperation Needed

Quick spray covers every tooth, no brushing required

Safe From First Tooth

Fluoride-free, alcohol-free, preservative-free, safe to swallow

PROTECTTHEIR TEETH THE EASY WAY

A Healthier Smile in Every Spray

Restore and protect your teeth on the go with CariSpray. Its nano-hydroxyapatite formula strengthens enamel, soothes sensitivity, and keeps your smile naturally radiant.

Happy Smiles, Real Results

CariSpray users experienced remarkable improvements—less staining, reduced tartar buildup, noticeably whiter teeth, and effortless daily use. A brighter, healthier smile starts with every spray.

0%

Less Staining

0%

Less Tartar Formation

0%

Reported Whiter and Brighter Teeth

0%

Found It Easy to Use

Caption: Proven by dentists — real smiles, real results!

Join 10,000+ People Who've Made the Switch to Smarter Oral Care

Professional-grade oral spray that balances oral pH and protects against cavities —backed by real results and a 30-day guarantee.

 Rated 4.8 stars by 10,000+ reviews
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CariSpray Nano-Hydroxyapatite Oral Spray

CariSpray Nano-Hydroxyapatite Oral Spray

Clinically proven oral spray that strengthens enamel and protects little teeth—no brushing needed.

🦷 Strengthen and Protect Your Enamel Naturally

💧 Refresh Your Smile with Every Simple Spray

🌿 Gentle Daily Formula for Sensitive Teeth

⚡ Fast-Acting Care for a Confident, Bright Smile

Regular price $38.99
Regular price $38.99 Sale price $58.99
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  • Pediatric Dentist Developed
CariSpray nano-hydroxyapatite oral spray benefits

CariSpray Nano-Hydroxyapatite Oral Spray

Regular price $38.99
Regular price $38.99 Sale price $58.99
SAVE 33% Sold out

Transform Your Oral Health with CariSpray Nano-Hydroxyapatite Oral Spray

CariSpray is a revolutionary nano-hydroxyapatite oral spray designed to strengthen teeth and support enamel health naturally. Our patent-pending formula provides 62% better enamel support in just 3 minutes, making it the most advanced oral care solution available.

What Makes CariSpray Different?

Our dentist-formulated spray uses nano-hydroxyapatite (n-HA), the same mineral that makes up 97% of your tooth enamel. Unlike traditional fluoride products, CariSpray works at the molecular level to support remineralization and neutralize the acids that cause decay.

Key Benefits:

  • Supports remineralization and strengthens tooth enamel
  • Provides 62% improved enamel support
  • Neutralizes harmful mouth acids with pH-balancing technology
  • Reduces tooth sensitivity within days
  • Restores natural whiteness without harsh abrasives
  • Safe to swallow - no rinsing required
  • Convenient spray format for protection anytime, anywhere

Clinically-Proven Results:

In a 30-day clinical study, CariSpray users reported:

  • 84% less staining
  • 73% less tartar buildup
  • 82% noticed whiter, brighter teeth
  • 100% found it easy to use

Premium Ingredients:

  • 0.46% Nano-Hydroxyapatite: Precisely formulated to replace daily mineral loss
  • 25% Xylitol: Supports a healthy oral microbiome
  • pH+ Buffering System: Sodium bicarbonate and potassium compounds that instantly balance mouth acidity

Who Should Use CariSpray?

Perfect for adults looking for advanced enamel support, enamel strengthening, sensitivity relief, or a fluoride-free oral care alternative. Ideal for use after meals, coffee, or whenever you need quick oral protection.

Professional-Quality Manufacturing:

CariSpray undergoes rigorous validation through accredited European laboratories following professional manufacturing protocols. All testing conducted under cGMP conditions for maximum safety and effectiveness.

How to Use:

Spray 2-3 times directly onto teeth after meals or as needed. No rinsing required. Safe to use throughout the day for continuous protection.

Made by Oral Advance Laboratories - Dentist developed, clinically proven, patent-pending technology.

Created by a Dentist
Developed by implantologist Dr. Martinčević to solve cavity problems in children—now available to everyone.

Science-Driven Innovation
We don't follow trends—we follow research. Every formula is built on clinical evidence and real-world results.

Balances Your Mouth's pH
CariSpray maintains optimal pH levels for healthy teeth and gums. No sugar, dyes, or harsh alcohol.

Key Benefits

🔬 Teeth Remineralization

Nano-hydroxyapatite penetrates enamel to rebuild tooth structure from within—strengthening teeth at the molecular level with every use.

✨ Restores Natural Whiteness

Nano-hydroxyapatite fills microscopic imperfections in enamel, smoothing the tooth surface to naturally reflect light and reveal your teeth's inherent brightness—without harsh bleaching agents.

🛡️ Protects Tooth Surface

Creates a protective mineral layer that shields enamel from daily acid exposure, wear, and environmental damage—strengthening your teeth's natural defenses with every spray.

🦷 Sensitivity Support

Helps seal exposed dentin tubules that cause sensitivity, providing gentle relief from hot, cold, and sweet triggers while supporting long-term enamel health.

We believe you shouldn’t keep getting cavities despite doing everything right.Brushing twice a day shouldn’t be the bare minimum — it should be enough.Modern diets and traditional oral care leave gaps — the hours between brushing,the pH swings from coffee, snacks, and stress, and the damage that happenswhile you sleep.That’s why we created CariSpray: professional-grade protectionthat works between the gaps. Real prevention that fits real life — whenever andwherever you need it.

PROFESSIONAL-GRADE FORMULA

Active Ingredients

CariSpray scientifically-backed formula contains:

  • Nano-Hydroxyapatite:
    The same mineral that makes up 97% of your tooth enamel. It remineralizes and strengthens teeth at the molecular level, using particles identical in size to those in natural teeth and bones—and in a concentration precisely matched to
    replace your teeth’s daily mineral loss.
  • Xylitol (25%): Clinically shown to support a balanced oral microbiome and help maintain a healthy mouth environment.
  • pH+ Buffering System: Sodium Bicarbonate and Potassium compounds that instantly balance
    mouth acidity

Supporting Ingredients

Our gentle,
alcohol-free base includes:
Water (Aqua), Glycerin, Polysorbate 20, Potassium Citrate, Potassium Chloride, Sodium Benzoate, Potassium Sorbate, natural flavor essences (Menthol, Citric Acid, Anethole, Beta-Caryophyllene), and citrus essential oils for fresh taste.

Usage Instructions

WHEN TO USE: After meals, snacks, coffee, before bedtime, or anytime you want stronger teeth and fresher breath.

What's NOT Inside

CariSpray is alcohol-free, fluoride-free, and contains no harsh chemicals, artificial dyes, or synthetic preservatives. Safe for daily use
by the whole family (ages 6+).

Pharmaceutical-Grade Clinical Validation & Purity Certification

CARISPRAY Adults has undergone rigorous validation through accredited European laboratories following pharmaceutical manufacturing protocols. The formulation received comprehensive analytical verification through ISO-certified testing facilities, establishing clinical-grade purity and biocompatibility standards.

 

Advanced Clinical Validation Protocol:

  • Sterile Microbiological Validation - Zero-tolerance pathogen screening with sub-detection levels (<10 CFU/ml) for all pathogenic organisms.
  •  Antimicrobial Preservation Efficacy - Challenge testing confirms our natural preservatives effectively protect against harmful bacteria, yeast, and mold. Tests show the formula successfully reduces dangerous microorganisms to safe levels and keeps them low over time, meeting European safety standards.
  • Dermatological Biocompatibility - Clinical patch testing on 20 hypersensitive subjects showing 100% negative reactivity, validated by a certified dermatologist MD, PhD.
  • European Pharmaceutical Compliance - Full regulatory compliance with EU Cosmetics Regulation (EC) No 1223/2009 and Bureau Veritas ISO 9001:2015 certification

All procedures conducted under cGMP conditions by accredited laboratories, including Meyer d.o.o., Dr Koziej Clinical Research Institute, and Croatian National Institute of Public Health.

The science you've been missing!

1. Scientifically Proven: Oral health that actually works. CariSpray patent pending technology and nano hydroxyapatite remineralization stops cavities before they start—replacing expensive dental visits at a fraction of the cost.

2. Professional-Grade Formula: The same technology dentists use, now in your pocket. Alcohol-free, gentle formula that doesn't burn or sting, yet delivers measurable pH balance immediately.

3. Instant & Portable: Designed for real life. Whether you're teaching, presenting, or simply between meals—just spray and go. Perfect discretion when you need it most.

4. No More Dental Anxiety: End the cycle of painful procedures and expensive treatments. See your mouth's pH transform in real-time. No guesswork, just pure protection



Manufactured in FDA-registered, family-safe facilities with specialized
pediatric quality controls.

Easy Directions for Little Hands

Instructions: Each bottle contains approximately 200 child-sized sprays. Use 2-3 sprays after any snack, meal, or sugary drink for comprehensive protection.

HOW TO USE (child-friendly visuals)

SHAKE • SPRAY • SMILE

1.     SHAKE well (fun for kids to help)

2.     SPRAY 2-3 times into the mouth, aiming at the teeth

3.     SWISH for 10-15 seconds

4.     Do not rinse with water afterward - let the protective ingredients work

5.     SMILE

WHEN TO USE: After meals or before bed, after snacks and treats, school or daycare use, travel and on-the-go protection, or anytime you want stronger teeth without the brushing battles.

Perfect for:

· Bedtime when brushing didn't happen

· After snacks and treats

· School or daycare use

· Travel and on-the-go protection

· Kids with sensory sensitivities

  • files/images_62.jpg

    “I started using CariSpray twice a day, and within a week my teeth felt smoother and cleaner. It’s so convenient after meals — no rinsing, no hassle, just lasting freshness.”

    Daniel M.
  • files/istockphoto-2157073181-612x612.jpg

    “As someone who drinks coffee daily, this spray has been a game changer. My enamel feels stronger, and my dentist even noticed less staining at my last visit.”

    Sophie R.
  • files/images_62.jpg

    “CariSpray fits perfectly into my busy routine. It keeps my mouth fresh and my teeth feeling stronger — a smart upgrade from regular mouthwash.”

    Alex T.
    View full details
    • Finally broke my cavity cycle after 30 years

      I’ve battled cavities for years despite perfect brushing. My dentist blamed low pH, so I tried this spray—6 weeks later, my pH normalized and for the first time in decades, I heard “no cavities”!

      Sarah K., Verified Purchase

    • Avoided my worst fear — more dental work

      I’ve had dental anxiety since a painful root canal, but using this daily gave me control again. My last visit was just a cleaning—no drilling, no bad news. For once, I’m not dreading the dentist!

      Mark D., Verified Purchase

    • A product backed by real science

      Getting my autistic son to cooperate with tooth brushing was impossible. This spray is so gentle and tastes good enough that he actually opens his mouth for it.

      Dr. Emily R.,

      CariSpray comparison showing superior cavity protection vs traditional products

      US VS. THEM COMPARISON

      Not another harsh mouthwash or temporary fix. Just dentist-developed pH science that actually prevents cavities.

      Martincevic Toni creator of carispray

      Hey, I'm Dr. Toni – a dentist, founder of OralAdvance Labs and creatorof CariSpray

      The moment that changed everything happened during a routine checkup. A 6-year-old named Luna needed her third filling in just one year. As I prepped the drill, her mom's voice cracked: "Doctor, I don't understand. We brush morning and night with fluoride toothpaste. We cut back on snacks and juice. I even bought those expensive kids' vitamins. What else can I possibly do?"

      Read Our Story

      Any last questions?

      What is CariSpray?

      CariSpray is the world’s first nano-hydroxyapatite oral spray, creating an entirely new category of oral care. It works through a triple mechanism: restoring pH balance, promoting microbiome optimization via xylitol, and enabling molecular-level tooth remineralization

      Yes. CariSpray is completely safe to
      swallow.

      The enamel on your teeth is composed of approximately 97% hydroxyapatite, and CariSpray’s 0.45% nano-hydroxyapatite concentration is carefully designed to replace the minerals your teeth naturally lose each day from dietary acids.

      Since these are biocompatible minerals already found in your body, swallowing the product poses no risk. No rinsing is necessary.

      OralAdvance partners with FLUIDINOVA,
      Europe’s leading manufacturer of high purity, research-grade nano hydroxyapatite.

      Key material specifications: Sub-100 nm rod-shaped particles 98% dentin tubule occlusion (vs. 82% for competitors) RDA <10 (extremely low abrasivity) Pharmaceutical-grade purity

      We use the only nano-hydroxyapatite approved by the EU's Scientific Committee on Consumer Safety as entirely safe, biocompatible, and non-toxic.

      CariSpray Kids uses calcium and phosphate minerals particles sized specificallyfor developing teeth, child-safe concentration levels, and natural fruitflavors kids actually want. The formulation is optimized for the unique needsof growing permanent teeth.The adult formulation have nano-hydroxiapatite.

      Yes – both clinical and laboratory studies confirm its effectiveness.

      30-Day Use Study Results:

      ✓ 84% less staining

      ✓ 73% less tartar buildup

      ✓ 82% of users said their teeth looked whiter and brighter

      ✓ 100% found it easy to use

      Laboratory Findings:

      • 62% improved cavity protection within just 3 minutes

      FLUIDINOVA Independent n-HA Research:

      • Complete dentin tubule sealing within 7 days

      • Sustained remineralization even after acid exposure

      • Electron microscopy confirms nano-hydroxyapatite particle integration into
      the enamel microstructure

      Research shows that up to 10–14% of enamel hydroxyapatite can be lost during cavity development in typical caries models lasting 15–30 days. This translates to an average daily mineral loss of approximately 0.67–0.93%.

      The 0.46% n-HA concentration in CariSpray is precisely formulated to replace this daily loss and maintain optimal mineral balance.

      Results occur at multiple levels: Immediate: Fresh breath and cleaner
      mouthfeel Within days: Improved oral pH balance After 2–4 weeks: Noticeable enamel smoothness and reduced sensitivity Long-term: Sustained remineralization
      and caries prevention

      Clinical data show measurable results
      within days: Immediate: Fresh breath and cleaner mouth sensation

      1 week: 35% reduction in tooth
      sensitivity

      2–4 weeks: Up to 80% reduction in
      sensitivity

      6 months: Up to 62% reduction in
      long-term hypersensitivity

      As validated in FLUIDINOVA’s independent
      research.

      Yes. Clinical imaging demonstrates natural
      whitening through remineralization.

      Electron microscopy shows nano hydroxyapatite particles smoothing the enamel surface, which enhances light reflection.

      Studies confirm that 50 nm particle sizes deliver optimal whitening and structural integration, as validated in FLUIDINOVA’s independent research.

      Because it mimics nature. Enamel and dentin naturally contain hydroxyapatite crystals about 40 nm in size. Our particles
      (<100 nm) are engineered to mirror this biological architecture, allowing them to bond seamlessly to the tooth surface for true biomimetic remineralization.

      CariSpray is the first oral
      spray to combine:

      pH balance restoration

      Xylitol-driven microbiome optimization

      Molecular-level enamel remineralization

      This triple-action approach revolutionizes
      preventive dental care.

      Yes. Suitable for ages 6 and up, our
      n-HA is SCCS-approved, 100% non toxic, paraben-free, vegan, and NATRUE-certified.

      CariSpray’s formula was developed from
      years of research and clinical validation.

      Compared to the cost of a single dental filling and other dental procedures, Carispray offers far greater long-term savings and protection.

      We offer a 30-day money-back guarantee.
      This window exceeds most dental treatment periods, providing enough time for measurable remineralization and relief outcomes to occur.